What is the likelihood that another biologic would be effective?  What is the likelihood that another biologic would be effective?

I have had RA for 37 years and have failed four biologics (Enbrel, Remicade, Orencia and Rituxan). My doctor wants to try Actemra. Is it worth trying? I have had numerous joint replacements and am worried about infection.

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Factors

It's true that both factor groups are possible; I had the same issue and once I consulted with my physician, it was determined that my response to biological therapy was not optimal because of interacting medical conditions.

All the best
Marisa Trevor
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